Hormone Replacement Therapy: Uses, Types, Risks & Benefits

By EaseMD Editorial · Updated Sept 30, 2025

Smiling woman learning about hormone replacement therapy

Hormone replacement therapy (HRT) is a treatment option for easing symptoms of menopause and helping restore hormone balance. At EaseMD, our goal is to provide clear, evidence-based information so you can make confident decisions about your health.

What is HRT?

HRT involves supplementing hormones that naturally decline during menopause—most often estrogen, sometimes progesterone, and occasionally testosterone. These therapies can reduce disruptive symptoms, improve quality of life, and support long-term well-being when prescribed appropriately.

Woman relaxing outdoors while considering HRT options

How does HRT work for menopausal women?

As estrogen levels decrease during perimenopause and menopause, the body experiences wide-ranging effects. By restoring hormone levels, HRT helps regulate functions tied to sleep, mood, temperature control, and bone density.

  • Hot flashes & night sweats
  • Sleep disruption
  • Low energy or brain fog
  • Vaginal dryness
  • Bone protection
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Types of HRT

Estrogen therapy

Usually recommended for women who have had a hysterectomy, available as pills, patches, creams, gels, and sprays.

Progesterone therapy

Prescribed for women with a uterus to lower the risk of endometrial cancer when using estrogen.

Combination therapy

Includes both estrogen and progesterone, commonly used for managing multiple symptoms.

Benefits of HRT

  • Relief from hot flashes and night sweats
  • Better sleep and reduced fatigue
  • Improved mood and mental clarity
  • Protection for bone health
  • Support for vaginal and urinary comfort

Health Risks Associated with HRT

  • Increased risk of blood clots (varies by delivery method)
  • Possible breast tenderness, bloating, or mild spotting
  • Small increased risk of certain cancers in long-term use
  • Not advised for those with a history of estrogen-sensitive cancers
Doctor reviewing treatment options with patient

Bioidentical HRT

Bioidentical hormones are chemically identical to those the body naturally produces. Many women prefer these options for their personalized approach and perceived tolerability. At EaseMD, we use evidence-based practices to guide safe, effective use of both bioidentical and traditional hormone therapies.

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This article is for informational purposes only and does not replace professional medical advice. Always consult with a qualified healthcare provider about your individual needs.